The Franck Lab group DCCT: a new way to visualize multiplexed coherence pathways in magnetic resonance data Water confined inside a reverse micelle Water confined inside a reverse micelle Mapping hydration water across the surface of the signaling protein K-Ras Probing water dynamics at the surface of a lipid bilayer Custom-built ESR/NMR instrumentation in the Franck Lab Site-directed spin labeling of the membrane protein proteorhodopsin Extracting spectral density information from ODNP measurements

The Franck Lab develops new magnetic-resonance-based spectroscopic techniques to see how water behaves at the nanoscale – at the surfaces of proteins, membranes, and other soft materials. This “hydration water” plays a central role in how these systems function, yet it remains remarkably difficult to observe directly. We draw on chemical physics, biochemistry, and custom instrument design to build tools that can watch it move.

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Our work is highly interdisciplinary and welcomes students from a wide range of backgrounds. The Franck Lab is open to working with talented graduate students, undergraduate researchers, and postdocs.

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